Not only that, as others have said, Akito loves the males of the family, any male in the family 'belongs' to her. She doesn't care if they are happily taken, as long as she can ruin the relationship, like she did with Hatori and Kana, she will be happy.
Ayame, he and his assitent get together, he loses the curse because of her, there are rumors that Shigure and Tohrus/Kyous/Yukis etc teacher will get together.
So Akito isn't liking the fact that he is losing power over the family, 'her' guys are now being taken away from her and she is near powerless to do anything about it. Akito might hate this but what can she do? The family no longer wanting to listen to her when it comes to this part of their lives.
They are, slowly, losing the curse one by one because of the people they fall in love with and wish to be with for the rest of their lives and Akito can do nothing. She might be head of the family but she is also the core of the family curse and with people losing their curse she can do nothing.
I know she doesn't deserve it with half the things she does towards the other family memebers but still, how can one fault her for the way she is? She was brought up this way, if anyone is to blame, then blame her mother.
Her parents saw she wasnt a male, she shouldnt of been head of the family so she made her what she is today...