+Anima is about a young boy named Cooro who is part of a race of people who are half animal.
Cooro is on a journey to find other +animas like himself. At the start of his journey he meets another +anima named Husky. While Cooro is part crow, Husky is part fish. Coor and Husky meet up while Husky is pretending to be a Mermaid Princess for money....
But Husky gets tied up and "kidnaped" by his boss, and so it's Cooro to the rescue. Cooro says that he will save Husky only if Husky goes on his journey with him. Husky agrees and so the two get away from the circus and go on their way to find more +anima.
Cooro can grow crow wings, Senri is able to make his right arm like a bear's, Husky is able to grow fins and gills like a fish, and Nana can grow bat ears and wings.